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Table 4 Risk factors for preterm complications and preterm delivery

From: A retrospective study for long-term oncologic and obstetric outcomes in cervical intraepithelial neoplasia treated with loop electrosurgical excision procedure: focus on surgical margin and human papillomavirus

 

Total (n = 31)

Preterm related complications

preterm birth

no (n = 17)

yes (n = 14)

P value

no (n = 23)

yes (n = 8)

P value

age at delivery

33.42 ± 3.94

33.04 ± 3.71

33.87 ± 4.29

0.567

33.88 ± 3.94

32.08 ± 3.86

0.274

parity at delivery

       

0

10 (32.26)

6 (35.29)

4 (28.57)

0.660

7 (30.43)

3 (37.5)

0.269

1

10 (32.26)

4 (23.53)

6 (42.86)

 

6 (26.09)

4 (50)

 

>=2

11 (35.48)

7 (41.18)

4 (28.57)

 

10 (43.48)

1 (12.5)

 

Previous preterm birth history

       

0

27 (87.1)

17 (100)

10 (71.43)

0.032

22 (95.65)

5 (62.5)

0.043

1

4 (12.9)

0 (0)

4 (28.57)

 

1 (4.35)

3 (37.5)

 

The duration between LEEP and delivery (day)

1149.94 ± 713.74

784.82 ± 314.76

1593.29 ± 817.09

0.009

1013.57 ± 585.25

1542 ± 932.71

0.214

preop HPV

       

Negative

27 (87.1)

13 (76.47)

14 (100)

0.108

19 (82.61)

8 (100)

0.550

Positive

4 (12.9)

4 (23.53)

0 (0)

 

4 (17.39)

0 (0)

 

Final Diagnosis

       

Negative(cervicitis)

2 (6.45)

2 (11.76)

0 (0)

0.239

2 (8.7)

0 (0)

1.000

LSIL

2 (6.45)

2 (11.76)

0 (0)

 

2 (8.7)

0 (0)

 

HSIL

27 (87.1)

13 (76.47)

14 (100)

 

19 (82.61)

8 (100)

 

Margin

       

 Negative

27 (87.1)

14 (82.35)

13 (92.86)

0.607

19 (82.61)

8 (100)

0.550

 Positive

4 (12.9)

3 (17.65)

1 (7.14)

 

4 (17.39)

0 (0)

 

 Exo (+)

2 (50)

2 (66.67)

0 (0)

 

2 (50)

  

 Endo (+)

1 (25)

0 (0)

1 (100)

 

1 (25)

  

 Both (+)

1 (25)

1 (33.33)

0 (0)

 

1 (25)

  

Postop HPV

       

Negative

22 (70.97)

12 (70.59)

10 (71.43)

1.000

15 (65.22)

7 (87.5)

0.379

Positive

9 (29.03)

5 (29.41)

4 (28.57)

 

8 (34.78)

1 (12.5)

 

excised lesion size

       

 Depth

1.04 ± 0.37

1.04 ± 0.4

1.04 ± 0.35

0.808

1.06 ± 0.37

0.98 ± 0.4

0.800

 Maximal length

2.63 ± 0.51

2.56 ± 0.43

2.71 ± 0.6

0.409

2.63 ± 0.48

2.62 ± 0.63

0.821