Table 3 Sensitivity, specificity, PPV, NPV, likelihood, and AUC

Margin status

Margin(+)

12/52

23.08 (13.72–36.13)

299/333

89.79 (86.07–92.6)

12/46

26.09 (15.6–40.26)

299/339

88.2 (84.33–91.21)

2.26 (1.253–4.076)

0.857 (0.735–0.999)

0.5643

(0.5043–0.6244)

Exo(+), Endo(-)

3/52

5.77 (1.98–15.64)

327/333

98.2 (96.13–99.17)

3/9

33.33 (12.06–64.58)

327/376

86.97 (83.19–90)

3.202 (0.826–12.41)

0.96 (0.896–1.028)

Exo(-), Endo(+)

9/52

17.31 (9.38–29.73)

310/333

93.09 (89.85–95.35)

9/32

28.13 (15.56–45.37)

310/353

87.82 (83.99–90.83)

2.506 (1.228–5.112)

0.888 (0.782–1.009)

Both (+)

0/52

0 (0–6.88)

328/333

98.5 (96.53–99.36)

0/5

0 (0–43.45)

328/380

86.32 (82.49–89.41)

1.015 (1.002–1.029)

HPV status (postop)

HPV+

39/52

75 (61.79–84.77)

254/333

76.28 (71.42–80.53)

39/118

33.05 (25.22–41.95)

254/267

95.13 (91.85–97.13)

3.161 (2.466–4.053)

0.328 (0.204–0.527)

0.7564

(0.697–0.8201)

HPV (+) and margin(+)

6/52

11.54 (5.4–22.97)

324/333

97.3 (94.94–98.57)

6/15

40 (19.82–64.25)

324/370

87.57 (83.81–90.55)

4.269 (1.585–11.499)

0.909 (0.823–1.005)

0.5442

(0.4995–0.5889)

HPV (+) and margin (-)

33/52

63.46 (49.87–75.2)

263/333

78.98 (74.28–83.01)

33/103

32.04 (23.81–41.56)

263/282

93.26 (89.72–95.64)

3.019 (2.252–4.047)

0.463 (0.322–0.665)

HPV (-) and margin (+)

6/52

11.54 (5.4–22.97)

308/333

92.49 (89.15–94.86)

6/31

19.35 (9.19–36.28)

308/354

87.01 (83.1–90.11)

1.537 (0.662–3.566)

0.956 (0.863–1.06)

HPV (-) and margin (-)

7/52

13.46 (6.68–25.27)

104/333

31.23 (26.49–36.4)

7/236

2.97 (1.44–5.99)

104/149

69.8 (62.01–76.6)

0.196 (0.098–0.391)

2.771 (2.287–3.358)