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Table 2 Predictors of CIN1 + recurrent or residual disease

From: A retrospective study for long-term oncologic and obstetric outcomes in cervical intraepithelial neoplasia treated with loop electrosurgical excision procedure: focus on surgical margin and human papillomavirus

 

Total

Event (%)

Univariate HR

Multivariate analysis

HR (95% CI)

P-value

HR (95% CI)

P-value

Age

 ≤ 40

154

16 (10.39)

1

   

 > 40

231

36 (15.58)

1.570 (0.870–2.835)

0.134

  

Menopause

 No

292

33 (11.3)

1

   

 Yes

93

19 (20.43)

1.992 (1.129–3.515)

0.017

  

Parity

 0

74

8 (10.81)

1

0.069

  

 1

75

4 (5.33)

0.463 (0.139–1.536)

0.208

  

 ≥ 2

236

40 (16.95)

1.468 (0.686–3.144)

0.323

  

Final Diagnosis

 Chronic cervicitis

19

3 (15.79)

1

0.973

  

 LSIL

20

2 (10)

0.843 (0.140–5.069)

0.852

  

 HSIL

346

47 (13.58)

0.998 (0.310–3.218)

0.998

  

Margin

 Negative

339

40 (11.8)

1

 

1

 

 Positive

46

12 (26.09)

1.952 (1.020–3.735)

0.043

1.948 (1.020–3.720)

0.043

  Exo (+)

9

3 (33.33)

2.782 (0.859–9.008)

0.088

  

  Endo (+)

32

9 (28.13)

2.061 (0.993–4.277)

0.052

  

  Both (+)

5

0 (0)

0.000 (0.000–0.000)

0.987

  

HPV status after LEEP

 Negative

267

13 (4.87)

1

 

1

 

 Positive

118

39 (33.05)

6.843 (3.650-12.827)

0.000

6.848 (3.652–12.840)

0.000