Table 1 Patient characteristics
Total (n = 385) | Margin (−) (n = 339) | Margin (+) (n = 46) | P-value | |
|---|---|---|---|---|
Age, years, mean ± SD | 43.81 ± 11.88 | 43.45 ± 11.78 | 46.41 ± 12.42 | 0.113 |
Age ≤ 40 | 154 (40) | 138 (40.71) | 16 (34.78) | 0.441 |
Age > 40 | 231 (60) | 201 (59.29) | 30 (65.22) | |
Menopause | ||||
No | 292 (75.84) | 260 (76.7) | 32 (69.57) | 0.289 |
Yes | 93 (24.16) | 79 (23.3) | 14 (30.43) | |
Parity | ||||
0 | 74 (19.22) | 68 (20.06) | 6 (13.04) | 0.508 |
1 | 75 (19.48) | 66 (19.47) | 9 (19.57) | |
≥ 2 | 236 (61.3) | 205 (60.47) | 31 (67.39) | |
HPV status before LEEP | ||||
Negative | 26 (6.75) | 26 (7.67) | 0 (0) | 0.071 |
Positive | 319 (82.86) | 280 (82.6) | 39 (84.78) | |
Unknown | 40 (10.39) | 33 (9.73) | 7 (15.22) | |
Cervical cytology before LEEP | ||||
Normal, RCC | 6 (1.56) | 6 (1.77) | 0 (0) | 0.072 |
ASCUS | 83 (21.56) | 76 (22.42) | 7 (15.22) | |
LSIL | 77 (20) | 72 (21.24) | 5 (10.87) | |
HSIL | 155 (40.26) | 134 (39.53) | 21 (45.65) | |
Etc | 64 (16.62) | 51 (15.04) | 13 (28.26) | |
Final diagnosis (worst) | ||||
Chronic cervicitis | 19 (4.94) | 18 (5.31) | 1 (2.17) | 0.516 |
LSIL | 20 (5.19) | 19 (5.6) | 1 (2.17) | |
HSIL | 346 (89.87) | 302 (89.09) | 44 (95.65) | |
HPV status after LEEP | ||||
Negative | 267 (69.35) | 236 (69.62) | 31 (67.39) | 0.759 |
Positive | 118 (30.65) | 103 (30.38) | 15 (32.61) | |
Cervical cytology after LEEP (worst) | ||||
Normal, RCC | 279 (72.47) | 253 (74.63) | 26 (56.52) | 0.070 |
ASCUS | 51 (13.25) | 41 (12.09) | 10 (21.74) | |
LSIL | 34 (8.83) | 28 (8.26) | 6 (13.04) | |
HSIL | 8 (2.08) | 7 (2.06) | 1 (2.17) | |
Etc | 13 (3.38) | 10 (2.95) | 3 (6.52) | |
f/u time (month), median(IQR) | 34.57 (12.20, 58.40) | 32.87 (12.17, 58.83) | 44.68 (33.30, 56.73) | 0.078 |