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Table 2 The OS and DFS of breast cancer molecular subtypes in different stages of the disease

From: Long-term outcomes of non-metastatic breast cancer patients by molecular subtypes

 

N

5-Years outcome

Mortality rate

N (%)

RR

N (%)

DMR

N (%)

OS

DFS

All patients

1287

134 (10.4)

53 (4.1)

82 (6.4)

86.3

79.3

HR+/Her2+

261

30 (11.5)

9 (3.4)

23 (8.8)

83.4

77.3

HR+/Her2−

658

47 (7.1)

17 (2.6)

47 (7.1)

90.2

84.2

HR−/Her2+

163

28 (17.2)

17 (10.4)

23 (14.1)

77.8

62.3

HR−/Her2−

205

29 (14.1)

10 (4.9)

19 (9.3)

81.0

76.5

p-valuea

    

 < 0.001

 < 0.001

Stage I

195

3 (1.5)

8 (4.1)

6 (3.1)

96.8

89.3

HR+/Her2+

31

2 (6.5)

1 (3.2)

2 (6.5)

89.2 +

63.1

HR+/Her2−

114

1 (0.9)

2 (1.8)

2 (1.8)

97.0

93.8

HR−/Her2+

17

0 (0)

3 (17.6)

2 (11.8)

90.0

47.7

HR−/Her2−

33

0 (0)

2 (6.1)

0 (0)

90.0

81.9

p-valuea

    

0.064

0.004

Stage II

681

56 (8.2)

30 (4.4)

55 (8.1)

88.6

82.2

HR+/Her2+

135

11 (8.1)

4 (3)

11 (8.1)

87.0

81.7

HR+/Her2−

351

16 (4.6)

11 (3.1)

21 (6)

92.8

87.3

HR−/Her2+

82

17 (20.7)

9 (11)

12 (14.6)

71.1

57.4

HR−/Her2−

113

12 (10.6)

6 (5.3)

11 (9.7)

83.9

79.2

p-valuea

    

 < 0.001

 < 0.001

Stage III

411

75 (18.2)

15 (3.6)

51 (12.4)

75.8

68.6

HR+/Her2+

95

17 (17.9)

4 (4.2)

10 (10.5)

73.9

69.1

HR+/Her2−

193

30 (15.5)

4 (2.1)

24 (12.4)

78.3

70.9

HR−/Her2+

64

11 (17.2)

5 (7.8)

9 (14.1)

76.7

62.0

HR−/Her2−

59

17 (28.8)

2 (3.4)

8 (13.6)

57.1

55.1

p-valuea

    

0.078

0.130

  1. N number of patients, RR recurrence rate, DMR distant metastasis rate, OS overall survival, DFS disease free survival
  2. a log-rank test