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Table 2 Genes with differential expression in human uterine fibroids identified by two or three groups of researchers.

From: DNA microarray data integration by ortholog gene analysis reveals potential molecular mechanisms of estrogen-dependent growth of human uterine fibroids

Accessiona

Symbolb

Gene Descritpionb

Hc

Tc

Wc

NM_007168

ABCA8

ATP-binding cassette, sub-family A (ABC1), member 8

-2.5

-5.7

 

NM_006720

ABLIM1

actin binding LIM protein 1

-3.3

-4.28

 

NM_000689

ALDH1A1

aldehyde dehydrogenase 1 family, member A1

-3.5

-7.98

-4

NM_000700

ANXA1

annexin A1

-4.1

-4.32

 

NM_001674

ATF3

activating transcription factor 3

-8.8

-6.04

 

M18767

C1S

complement component 1, s subcomponent

-2.5

 

-3.2

NM_004772

C5orf13

chromosome 5 open reading frame 13

2.45

2.81

 

NM_001218

CA12

carbonic anhydrase XII

3.81

4.8

 

U17473

CALCRL

calcitonin receptor-like receptor

-2.1

 

-1.7

NM_001870

CPA3

carboxypeptidase A3 (mast cell)

-2.1

-8.18

 

NM_001878

CRABP2

cellular retinoic acid binding protein 2

3.05

5.12

2.6

AF003114

CYR61

cysteine-rich, angiogenic inducer, 61

-5.8

-5.3

 

AI826799

EFEMP1

EGF-containing fibulin-like extracellular matrix protein 1

-4.1

-4.51

-5

BC004490

FOS

v-fos FBJ murine osteosarcoma viral oncogene homolog

-9.5

-8.17

 

NM_007003

GAGEC1

G antigen, family C, 1

2.98

40.7

 

NM_000826

GRIA2

glutamate receptor, ionotropic, AMPA 2

7.48

38.8

4.9

J03242

IGF2

insulin-like growth factor 2 (somatomedin A)

 

16.8

2.6

NM_002178

IGFBP6

insulin-like growth factor binding protein 6

-4.5

-5.26

 

NM_004522

KIF5C

kinesin family member 5C

2.12

9.02

 

AL021977

MAFF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)

-6.8

-3.38

 

NM_005923

MAP3K5

mitogen-activated protein kinase kinase kinase 5

-2.1

-4.13

-3

NM_002402

MEST

mesoderm specific transcript homolog (mouse)

3.87

11.6

2.4

NM_002135

NR4A1

nuclear receptor subfamily 4, group A, member 1

-3.7

-3.78

 

NM_006198

PCP4

Purkinje cell protein 4

4.85

8.23

 

AI934473

PIK3R1

phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)

3.01

2.21

 

BC002665

PLP1

proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated)

4.75

12.1

 

BC005939

PTGDS

prostaglandin D2 synthase 21kDa (brain)

-2

-3.47

-2

D86096

PTGER3

prostaglandin E receptor 3 (subtype EP3)

 

-4.2

-2.8

NM_002937

RNASE4

ribonuclease, RNase A family, 4

-2

-3.38

 

U89281

RODH

3-hydroxysteroid epimerase

1.93

3.34

 

NM_000602

SERPINE1

serine (or cysteine) proteinase inhibitor, clade E, member 1

-4.4

-4.09

 

BG528420

SOX4

SRY (sex determining region Y)-box 4

3.98

2.81

 

NM_003242

TGFBR2

transforming growth factor, beta receptor II

-1.8

-2.02

 

NM_021992

TMSNB

thymosin, beta, identified in neuroblastoma cells

1.59

5.51

 

NM_007116

TNXB

tenascin XB

-2.2

-6.28

 

NM_003294

TPSB2

tryptase beta 2

-4.1

-24.3

 

AF349719

TRO

trophinin

1.74

3.3

 

NM_001071

TYMS

thymidylate synthetase

2.1

9.12

3.3

  1. a Genbank or RefSeq accession number.
  2. b Gene symbol or description were obtained from the BioConductor Project.
  3. c Fold change of gene expression in uterine fibroids vs myometrium. H, T and W represent studies by Hoffman et al. [18], Tsibris et al. [14] and Wang et al. [17] respectively.